Vidya Balan won several awards for her flawless performance in Ishqiya. However, Madhuri was her replacement in the sequel Dedh Ishqiya.
Mallika Sherawat and Rahul Bose were replaced by Vidya Balan and Farhan Akhtar in the sequel of Shaadi Ke Side Effects.
Akshay Kumar was replaced in the sequel Welcoe Back by John Abraham.
Shreyash Talpade replaced Sharman Joshi in the Golmaal sequel named Golmaal Returns.
Ali Zafar was replaced in Sequel Tere Bin Laden : Dead or Alive by Manish Paul.
Divyendu Sharma and Raayo S Bakhirta were replacesd by Omkar Kapoor and Sunny Singh in Pyaar Ka Punchnama 2.
Arshad Warsi was replaced by Akshay Kumar in the sequel Jolly LL.B 2.
Aman Siddiqui was replacedby Parth Bhalerao in the sequel Bhoothnath Returns.